Hydroxypropyl Methyl Cellulose (HPMC)
Product Description
Hydroxypropyl methyl cellulose (HPMC) or hypromellose, is a cellulose-based polymer for film coating, wet granulation, and hard capsule manufacturing. It is practically insoluble in hot water, anhydrous ethanol, and dissolves in cold water, resulting in a colloidal solution.
Product Properties
1 . Resistance to salting : Hydroxypropyl methyl cellulose (HPMC) is a nonionic cellulose ether and it is not a polyelectrolyte . The aqueous solution of Hydroxypropyl methyl cellulose (HPMC) is comparatively stable even in the presence of metal salts or organic electrolytes . However, when the concentration of electrolytes exceeds a certain limit, gelation and precipitation may result .
2 . Surface activity : An aqueous solution of Hydroxypropyl methyl cellulose (HPMC) has a high surface activity and functions as a protective colloid agent , emulsion stabilizer and dispersant .
3 . Thermal gelation :An aqueous solution of Hydroxypropyl methyl cellulose (HPMC) will gel or precipitate when heated to a certain temperature , but it reverts to the original solution state on subsequent cooling . The temperature at which gelation or precipitation occur depends on the type of HPMC , its concentration and the rate of heating .
4 . pH stability :The viscosity of an aqueous solution of HPMC is hardly affected by acid or alkali , and the product can develop an original viscosity in the range of 3 . 0~11 . 0 . Therefore , the solution viscosity tends to keep stable during prolonged storage .
5. Water retention :Hydroxypropyl methyl cellulose (HPMC) is a high effective water retention agent . Its pharmaceutical grade product can be widely used in food, cosmetics and many other fields .
6 . Film forming :Hydroxypropyl methyl cellulose (HPMC) provides a strong , flexible and transparent film having a good barrier property against oil and grease .In food application , this property is often utilized for water retention and oil adsorption .
7 . Cohesiveness (Binding property) : Hydroxypropyl methyl cellulose (HPMC) , as a high performance binder, can also be used for molding food and medicine .
Technical Index
Table 1
Item
|
Specifications |
HPMC |
F |
E |
J |
K |
Loss on drying, %
|
5.0MAX |
Residue on ignition,% |
1.5MAX |
Heavy metals,ppm |
20MAX |
PH |
5.0~8.0 |
Bacterium |
1000cfu/gram MAX |
Mold |
100cfu/gram MAX |
Viscosity (2% solution),mPa.s |
refer to Table 2 |
Table 2
Level |
Specific range (mPa.s) |
Level |
Specific range (mPa.s) |
5 |
4~9 |
8000 |
6000~9000 |
15 |
10~20 |
10000 |
9000~12000 |
25 |
20~30 |
15000 |
12000~18000 |
50 |
40~60 |
20000 |
18000~30000 |
100 |
80~120 |
40000 |
30000~50000 |
400 |
300~500 |
75000 |
50000~85000 |
800 |
600~900 |
100000 |
85000~130000 |
1500 |
1000~2000 |
150000 |
130000~180000 |
4000 |
3000~5600 |
200000 |
≥180000 |
*Any other special requirement for the product can be satisfied through the negotiation between Supplier and Buyer.
Application

Hydroxypropyl methyl cellulose (HPMC) is used as adhesive, solutizer in tablet, film-forming reagents in pharmaceutical coating,delayed-release and controlled-release tablets or capsules, thickener and water-binding agent in liquid formulation, component in eye drop.
Packaging & Shipping
With pallet 25kg/drum 25kg/bag
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