Customization: | Available |
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CAS No.: | 9004-65-3 |
Formula: | C3h7o |
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1 . Resistance to salting : Hydroxypropyl methyl cellulose (HPMC) is a nonionic cellulose ether and it is not a polyelectrolyte . The aqueous solution of Hydroxypropyl methyl cellulose (HPMC) is comparatively stable even in the presence of metal salts or organic electrolytes . However, when the concentration of electrolytes exceeds a certain limit, gelation and precipitation may result .
2 . Surface activity : An aqueous solution of Hydroxypropyl methyl cellulose (HPMC) has a high surface activity and functions as a protective colloid agent , emulsion stabilizer and dispersant .
3 . Thermal gelation :An aqueous solution of Hydroxypropyl methyl cellulose (HPMC) will gel or precipitate when heated to a certain temperature , but it reverts to the original solution state on subsequent cooling . The temperature at which gelation or precipitation occur depends on the type of HPMC , its concentration and the rate of heating .
4 . pH stability :The viscosity of an aqueous solution of HPMC is hardly affected by acid or alkali , and the product can develop an original viscosity in the range of 3 . 0~11 . 0. Therefore , the solution viscosity tends to keep stable during prolonged storage .
5. Water retention :Hydroxypropyl methyl cellulose (HPMC) is a high effective water retention agent.
6 . Film forming :Hydroxypropyl methyl cellulose (HPMC) provides a strong , flexible and transparent film having a good barrier property against oil and grease .In food application, this property is often utilized for water retention and oil adsorption .
7 . Cohesiveness (Binding property) : Hydroxypropyl methyl cellulose (HPMC) as a high performance binder, can also be used for molding food and medicine .
Item |
Specifications | |||
HPMC | ||||
F | E | J | K | |
Loss on drying, % |
5.0MAX | |||
Residue on ignition,% | 1.5MAX | |||
Heavy metals,ppm | 20MAX | |||
PH | 5.0~8.0 | |||
Bacterium | 1000cfu/gram MAX | |||
Mold | 100cfu/gram MAX | |||
Viscosity (2% solution),mPa.s | refer to Table 2 |
Level | Specific range (mPa.s) | Level | Specific range (mPa.s) |
5 | 4~9 | 8000 | 6000~9000 |
15 | 10~20 | 10000 | 9000~12000 |
25 | 20~30 | 15000 | 12000~18000 |
50 | 40~60 | 20000 | 18000~30000 |
100 | 80~120 | 40000 | 30000~50000 |
400 | 300~500 | 75000 | 50000~85000 |
800 | 600~900 | 100000 | 85000~130000 |
1500 | 1000~2000 | 150000 | 130000~180000 |
4000 | 3000~5600 | 200000 | ≥180000 |
Usage | Applicable type of the product | Typical Use Level |
Bulk Laxative | K-4000,K-100,000 | 3-30% |
Creams, Gels, and Ointments | E-4000,F-4000,K-4000 | 1-5% |
Ophthalmic Preparations | E-4000 | 01.-0.5% |
Eye drops preparations | F-4000, K-4000 | 0.1-0.5% |
Suspending agent | E-4000, K-4000 | 1-2% |
Antacids | E-4000,K-4000,K-15000,F-4000 | 1-2% |
Tablets binder | E-5, F-50, K-100 | 0.5-5% |
Conventional Tablet Coating | E-5,E-15 | 0.5-5% |
Conventional Wet Granulation | E-5,E-15 | 2-6% |
Controlled Release Coatings | E-5,E-15 | 3-20% |
Tablet coatings | E-5, E-15, E-50 | 0.5-5% |
Controlled Release Matrix Tablets | K-100,000,K-15,000,K-4000,E-4000 | 20-55% |
The product is packed in polyethylene bag enclosed in composite fiberboard drum or paper bag.
The net weight is 25 kg/drum or 25 kg/bag .
The product should be kept in the original bag and stored in the dry and clean place far away from the source of heat and not put together with other chemicals.