Pharma Grade HPMC Hydroxypropyl Methyl Cellulose for Control Release Tablet

• Customization: Available
• CAS No.: 9004-65-3
• Formula: C3h7o
• Model NO.: E5 E15
• EINECS: 618-389-6
• Appearance: Powder
• Usage: Food Grade
• Color: White
• Transport Package: 25kg/Bag/Drum
• Specification: E5 E15 K100M
• Trademark: Honest
• Origin: China
• HS Code: 3912900000
• Production Capacity: 8000 Tons/Year

Product Description

 

Product Description

Hydroxypropyl methyl cellulose (HPMC) or hypromellose, HPMC is odorless, tasteless,non-toxic cellulose ethers producted from natural hIgh molecular cellulose through series of chemical processing and achieved.

As a film forming polymer our product Hydroxypropyl Methyl Cellulose(HPMC) is the ideal material for empty capsule shell. Empty capsule shelL produce by our HPMC has the properties of low moisture content, superior stabilities, high filling rate.

Product Properties

1 . Resistance to salting : Hydroxypropyl methyl cellulose (HPMC) is a nonionic cellulose ether and it is not a polyelectrolyte . The aqueous solution of Hydroxypropyl methyl cellulose (HPMC) is comparatively stable even in the presence of metal salts or organic electrolytes . However, when the concentration of electrolytes exceeds a certain limit, gelation and precipitation may result .

2 . Surface activity : An aqueous solution of Hydroxypropyl methyl cellulose (HPMC) has a high surface activity and functions as a protective colloid agent , emulsion stabilizer and dispersant .

3 . Thermal gelation :An aqueous solution of Hydroxypropyl methyl cellulose (HPMC) will gel or precipitate when heated to a certain temperature , but it reverts to the original solution state on subsequent cooling . The temperature at which gelation or precipitation occur depends on the type of HPMC , its concentration and the rate of heating .

4 . pH stability :The viscosity of an aqueous solution of HPMC is hardly affected by acid or alkali , and the product can develop an original viscosity in the range of 3 . 0~11 . 0 . Therefore , the solution viscosity tends to keep stable during prolonged storage .

5. Water retention :Hydroxypropyl methyl cellulose (HPMC) is a high effective water retention agent . Its pharmaceutical grade product can be widely used in food, cosmetics and many other fields .

6 . Film forming :Hydroxypropyl methyl cellulose (HPMC) provides a strong , flexible and transparent film having a good barrier property against oil and grease .In food application , this property is often utilized for water retention and oil adsorption .

7 . Cohesiveness (Binding property) : Hydroxypropyl methyl cellulose (HPMC) , as a high performance binder, can also be used for molding food and medicine .

Technical Index

Table 1

Item	Specifications
	HPMC
	F	E	J	K
Loss on drying, %	5.0MAX
Residue on ignition,%	1.5MAX
Heavy metals,ppm	20MAX
PH	5.0~8.0
Bacterium	1000cfu/gram MAX
Mold	100cfu/gram MAX
Viscosity (2% solution),mPa.s	refer to Table 2

Table 2

Level	Specific range (mPa.s)	Level	Specific range (mPa.s)
5	4~9	8000	6000~9000
15	10~20	10000	9000~12000
25	20~30	15000	12000~18000
50	40~60	20000	18000~30000
100	80~120	40000	30000~50000
400	300~500	75000	50000~85000
800	600~900	100000	85000~130000
1500	1000~2000	150000	130000~180000
4000	3000~5600	200000	≥180000

*Any other special requirement for the product can be satisfied through the negotiation between Supplier and Buyer.

Application

Hydroxypropyl methyl cellulose (HPMC) is used as adhesive, solutizer in tablet, film-forming reagents in pharmaceutical coating,delayed-release and controlled-release tablets or capsules, thickener and water-binding agent in liquid formulation, component in eye drop. 

Packaging & Shipping

                   
             

The product is packed in polyethylene bag enclosed in composite fiberboard drum or paper bag.
The net weight is 25 kg/drum or 25 kg/bag  .
The product should be kept in the original bag and stored in the dry and clean place far away from the source of heat and not put together with other chemicals.

 

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